A potent immunoregulator that suppresses IgE production. Suppresses innate immunity by down-regulating TLR2, TLR4 and CD14 gene expression on splenocytes stimulated with LPS and TLR2/TLR4 agonists. Prevents bleomycin-induced pulmonary fibrosis in mouse models. Potent inhibitor of Th2 cells in...
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A potent immunoregulator that suppresses IgE production. Suppresses innate immunity by down-regulating TLR2, TLR4 and CD14 gene expression on splenocytes stimulated with LPS and TLR2/TLR4 agonists. Prevents bleomycin-induced pulmonary fibrosis in mouse models. Potent inhibitor of Th2 cells in vivo and together with a Treg cell inhibitor promotes BCG vaccine efficacy against tuberculosis. Antiasthmatic agent effective for antileukotriene nonresponders. Orally active
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