Potent selective inhibitor of VEGFR kinase (also known as Flk-1 and KDR). Inhibition of the activated kinase (IC50 = 0.4 µM) is 100-fold less than inhibition of the unactivated kinase (IC50 = 0.04 µM). Also inhibits PDGFR kinase (IC50 = 19.4 µM)
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Potent selective inhibitor of VEGFR kinase (also known as Flk-1 and KDR). Inhibition of the activated kinase (IC50 = 0.4 µM) is 100-fold less than inhibition of the unactivated kinase (IC50 = 0.04 µM). Also inhibits PDGFR kinase (IC50 = 19.4 µM)
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