Broad-spectrum cytochrome P450 monoxygenase inhibitor that also blocks the acetylcholine receptor (IC50 = 19 µM). Inhibits nitric oxide synthase (NOS). Also inhibits glibenclamide-sensitive K+ channels (IC50 = 9.8 µM) in Xenopus oocytes. Increases inflammatory cytokine expression in Müller glial...
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Broad-spectrum cytochrome P450 monoxygenase inhibitor that also blocks the acetylcholine receptor (IC50 = 19 µM). Inhibits nitric oxide synthase (NOS). Also inhibits glibenclamide-sensitive K+ channels (IC50 = 9.8 µM) in Xenopus oocytes. Increases inflammatory cytokine expression in Müller glial cells and inhibits the excitability of rat 5-HT neurons
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