Pan-prolyl hydroxylase domain (PHD) inhibitor (IC50 for PHD2 = 591 nM) that stabilizes hypoxia-inducible factor (HIF) leading to erythropoiesis. Clinically useful for treatment of anemia related to chronic kidney disease. Accelerates cutaneous wound healing and shortens healing time via...
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Pan-prolyl hydroxylase domain (PHD) inhibitor (IC50 for PHD2 = 591 nM) that stabilizes hypoxia-inducible factor (HIF) leading to erythropoiesis. Clinically useful for treatment of anemia related to chronic kidney disease. Accelerates cutaneous wound healing and shortens healing time via improvement in epidermal stem cell proliferation and motility and increasing angiogenesis. Displayed radioprotective effects in haematopoietic systems via up-regulation of HIF-1α, and against atherosclerosis via activation of adipose HIF-2α
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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