Potent and selective inhibitor of cyclin-dependent kinases displaying higher potency and selectivity compared to olomoucine. p34 cdc2 IC50 = 0.2 µM. Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic. Prevents PPARγ S273 phosphorylation, promoting browning of white adipose tissue. Enhances...
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Potent and selective inhibitor of cyclin-dependent kinases displaying higher potency and selectivity compared to olomoucine. p34 cdc2 IC50 = 0.2 µM. Also inhibits p33cdk2 and p33cdk5. Anti-angiogenic. Prevents PPARγ S273 phosphorylation, promoting browning of white adipose tissue. Enhances peripheral nerve regrowth
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