RGFP966 is a selective inhibitor of HDAC3 (IC50 = 80 nM, no other HDACs inhibited at 15µM). It facilitates the extinction of cocaine-seeking behavior in mice and transforms subthreshold learning events into robust long-term memory, suggesting a potential therapeutic target for memory enhancement...
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RGFP966 is a selective inhibitor of HDAC3 (IC50 = 80 nM, no other HDACs inhibited at 15µM). It facilitates the extinction of cocaine-seeking behavior in mice and transforms subthreshold learning events into robust long-term memory, suggesting a potential therapeutic target for memory enhancement and neurodegenerative diseases
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