A Toll-like receptor 7/8 agonist. May be used as an immune adjuvant in cancer vaccines. Resiquimod-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Topical treatment of...
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A Toll-like receptor 7/8 agonist. May be used as an immune adjuvant in cancer vaccines. Resiquimod-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Topical treatment of wild-type mice induces systemic autoimmune disease which may be used as a model of systemic Lupus erythematosus. Effect on stem cells depends on cell type5,6
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