Inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil. It is also an inhibitor of the methyltransferase G9a (IC 50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment...
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Inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil. It is also an inhibitor of the methyltransferase G9a (IC 50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer’s disease
Solutions in DMSO may be stored under an inert atmosphere at -20°C for up to 3 months
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