Selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. Inhibits p53 binding to antiapoptotic proteins Bcl-xL and Bcl-2. Recues primary mouse thymocytes from P53-mediated apoptosis induced by radiation. Inhibits autophagy and enhances the...
Know who made it. See the evidence. Buy through one marketplace.
Selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. Inhibits p53 binding to antiapoptotic proteins Bcl-xL and Bcl-2. Recues primary mouse thymocytes from P53-mediated apoptosis induced by radiation. Inhibits autophagy and enhances the antitumor effect of TRAIL on human pancreatic cancer. Induces p53-independent apoptosis in B-chronic lymphocytic leukemia cells. Cell permeable
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
HSPA1A identifies heat shock protein family A (Hsp70) member 1A in Homo sapiens (Human). This target record connects NCBI Gene 3303, UniProtKB P0DMV8 and related ABMIUM catalogue products.
