Reversible inhibitor of Ca 2+ -independent phospholipase A 2 (PLA 2 ), IC50=7 μM for guinea pig lung PLA2. Inhibits epinephrine-induced thromboxane production in platelets. Inhibition of PLA 2 by ONO-RS-032 disrupts endosome tubule formation and maintenance of the Golgi complex. Prevents Xenopus...
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Reversible inhibitor of Ca 2+ -independent phospholipase A 2 (PLA 2 ), IC50=7 μM for guinea pig lung PLA2. Inhibits epinephrine-induced thromboxane production in platelets. Inhibition of PLA 2 by ONO-RS-032 disrupts endosome tubule formation and maintenance of the Golgi complex. Prevents Xenopus oocyte maturation at stage V
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