Upregulates the transcription factor NRF2 and prevents insulin resistance and obesity induced by high fat diet in C57BL/6J mice. Attenuates the progression of fibrosis in a rat model of nonalcoholic steatohepatitis. Attenuates chronic hypoxia-induced cardiopulmonary alterations in mice. Promotes...
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Upregulates the transcription factor NRF2 and prevents insulin resistance and obesity induced by high fat diet in C57BL/6J mice. Attenuates the progression of fibrosis in a rat model of nonalcoholic steatohepatitis. Attenuates chronic hypoxia-induced cardiopulmonary alterations in mice. Promotes liver regeneration after partial hepatectomy. Off target effects: Activates constitutive androstane receptor (CAR)
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NFE2L2 identifies NFE2 like bZIP transcription factor 2 in Homo sapiens (Human). This target record connects NCBI Gene 4780, UniProtKB Q16236 and related ABMIUM catalogue products.
