Inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of stemness-high cancer cells isolated from a variety of cancer types. Effective antitumor agent as a monotherapy or in combination with other agents such as taxol in mouse models....
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Inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of stemness-high cancer cells isolated from a variety of cancer types. Effective antitumor agent as a monotherapy or in combination with other agents such as taxol in mouse models. Clinical trials have demonstrated encouraging anti-tumor activity with the potential to suppress metastasis and prevent relapse in patients with various types of cancer. Overcomes cisplatin resistance in non-small cell lung cancer
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