Muscone is a macrocyclic ketone found naturally in a glandular secretion of the musk deer which acts at human odorant receptor OR5AN1 and is used in perfumes. It suppresses inflammatory responses and neuronal damage in various models including a rat model of cervical spondylotic myelopathy and...
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Muscone is a macrocyclic ketone found naturally in a glandular secretion of the musk deer which acts at human odorant receptor OR5AN1 and is used in perfumes. It suppresses inflammatory responses and neuronal damage in various models including a rat model of cervical spondylotic myelopathy and relieves inflammatory pain acting via the NOX4/JAK2-STAT3 and NLRP3 inflammasome pathway. In the cardiovascular system it alleviates myocardial ischemia-reperfusion injury and improves cardiac function in mice after myocardial infarction via enhancement of angiogenesis
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