Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4) displaying inverse agonist activity, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes. Selective for the CysLT1 receptor. Multidrug resistance protein 1 (MRP1) inhibitor
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Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4) displaying inverse agonist activity, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes. Selective for the CysLT1 receptor. Multidrug resistance protein 1 (MRP1) inhibitor
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