Lonidamine is an antiglycolytic drug with limited efficacy. Mito-lonidamine is lonidamine conjugated to a triphenylphosphonium moiety via a decyl-linker which is an effective mitochondria-targeting group. Mito-lonidamine was shown to be100-fold more potent than lonidamine. It is a...
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Lonidamine is an antiglycolytic drug with limited efficacy. Mito-lonidamine is lonidamine conjugated to a triphenylphosphonium moiety via a decyl-linker which is an effective mitochondria-targeting group. Mito-lonidamine was shown to be100-fold more potent than lonidamine. It is a tumor-selective inhibitor of oxidative phosphorylation inhibiting mitochondrial bioenergetics in lung cancer cells and suppressing lung cancer cell viability, growth, progression and metastasis of lung cancer xenografts in mice
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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