Manufactured by:TriBio Science
RUO

Leonurine, Neuroinflammation inhibitor

Inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways. Inhibits the formation of advanced glycation end products. Ameliorates cognitive dysfunction by antagonizing exocytotoxic glutamate insults and inhibiting autophagy....

SKU:
ABM147264-1
Manufacturer SKU
TBI3193-10MG | TBI3193-50MG
Product type
Biochemical Inhibitors
TargetNeuroinflammation
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways. Inhibits the formation of advanced glycation end products. Ameliorates cognitive dysfunction by antagonizing exocytotoxic glutamate insults and inhibiting autophagy. Attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4. Attenuates early atherosclerotic lesions in hypercholest-erolemic rabbits via modulation of the inflammatory and oxidative stress pathways

Key facts & specifications
Also known as
SCM-198
Molecular weight
311.33
Form / buffer
powder
Activity
Inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-κB pathways. Inhibits the formation of advanced glycation end products. Ameliorates cognitive dysfunction by antagonizing exocytotoxic glutamate insults and inhibiting autophagy. Attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4. Attenuates early atherosclerotic lesions in hypercholest-erolemic rabbits via modulation of the inflammatory and oxidative stress pathways.
Molecular formula
C 14 H 21 N 3 O 5
Solubility
Soluble in DMSO (up to 30 mg/ml).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI3193-10MG | TBI3193-50MG
CAS number
24697-74-3
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£78.00