Glutamate dehydrogenase (GDH) is a mitochondria enzyme and related to amino acids metabolism. GDH is involved in the metabolism of glutamate, which is essential for neurotransmitter recycling and overall brain function. Elevated levels of GDH in the blood can indicate liver damage, and its...
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Glutamate dehydrogenase (GDH) is a mitochondria enzyme and related to amino acids metabolism. GDH is involved in the metabolism of glutamate, which is essential for neurotransmitter recycling and overall brain function. Elevated levels of GDH in the blood can indicate liver damage, and its activity is often used in clinical diagnostics. Dysfunction of GDH is linked to conditions such as Parkinson’s disease, schizophrenia, and frontotemporal dementia
Tribio™ Glutamate dehydrogenase (GDH) activity Quantification Colorimetric Assay is based on a dehydrogenase coupled reaction convert chromophore to a colored formazan, which can be measured at OD 460 nm. The generated signal is proportional to the content of NADPH. This assay specifically detects GDH activity from the cell lysate. The kit provides the easiest and most accurate approach to measure GDH activity from a variety of samples
Specifically detect glutamate dehydrogenase activity from cell and biological tissues
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Sample compatibility |
|---|---|
| Cell lysate |
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
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