Potent and selective PKCβ inhibitor. IC50 = 6, 39, 83 and 110 nM, for PKCβ, PKCα, PKCγ and PKCε respectively. Induces apoptosis in multiple myeloma cell lines via inhibition of the AKT signaling pathway. Induces mitotic missegregation and preferential cytotoxicity in colorectal cancer cells with...
Know who made it. See the evidence. Buy through one marketplace.
Potent and selective PKCβ inhibitor. IC50 = 6, 39, 83 and 110 nM, for PKCβ, PKCα, PKCγ and PKCε respectively. Induces apoptosis in multiple myeloma cell lines via inhibition of the AKT signaling pathway. Induces mitotic missegregation and preferential cytotoxicity in colorectal cancer cells with chromosomal instability. Attenuates ampheta-mine-stimulated dopamine efflux. Inhibits blood-brain barrier leakiness in a mouse model
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
