Deltamethrin is reported to be an inhibitor of calcineurin (PP2B), IC 50 ~100 pM but this activity has been disputed. Markedly enhances the expression of BDNF in cultured rat cortical neurons and displays neurotrophic effects. Produces antidepressant-like effects in mice. Blocks the spontaneous...
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Deltamethrin is reported to be an inhibitor of calcineurin (PP2B), IC 50 ~100 pM but this activity has been disputed. Markedly enhances the expression of BDNF in cultured rat cortical neurons and displays neurotrophic effects. Produces antidepressant-like effects in mice. Blocks the spontaneous down-regulation of Nav1.8 sodium channels expressed in Xenopus oocytes
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