Potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM. The first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Promotes proliferation in mammalian cardiomyocytes A potent inhibitor of malignant lymphoid cell proliferation
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Potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3) IC50=5 nM. The first pharmacological agent shown to maintain self-renewal in human and mouse embryonic stem cells. Promotes proliferation in mammalian cardiomyocytes A potent inhibitor of malignant lymphoid cell proliferation
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