(±)12(13)-DiHOME ELISA Kit is a research-use competitive ELISA for quantitative measurement of (±)12(13)-DiHOME. (±)12(13)-DiHOME is the vicinal diol metabolite of (±)12(13)-EpOME (i.e., isoleukotoxin), an epoxide derived from linoleic acid via cytochrome P450 epoxygenase activity. It has been...
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(±)12(13)-DiHOME ELISA Kit is a research-use competitive ELISA for quantitative measurement of (±)12(13)-DiHOME.
(±)12(13)-DiHOME is the vicinal diol metabolite of (±)12(13)-EpOME (i.e., isoleukotoxin), an epoxide derived from linoleic acid via cytochrome P450 epoxygenase activity. It has been shown to suppress neutrophil respiratory burst activity and exhibit selective cytotoxicity in certain cell lines expressing sEH. Thus, (±)12(13)-DiHOME bridges lipid metabolism and immune modulation, acting both as a downstream stress-responsive signal and as a paracrine regulator in inflammation and energy homeostasis
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