VCAM1 polyclonal antibody; host Rabbit; reactivity Human, Rat, Mouse
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vascular cell adhesion molecule 1(VCAM1) Homo sapiens This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010],
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species / reactivity | WB | ELISA |
|---|---|---|
| Human,Rat,Mouse |
This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
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VCAM1 identifies vascular cell adhesion molecule 1 in Homo sapiens (Human). This target record connects NCBI Gene 7412, UniProtKB P19320 and related ABMIUM catalogue products.
Biological function: VCAM1 is an endothelial cell-adhesion glycoprotein that regulates leukocyte adhesion and transendothelial migration through interactions with leukocyte integrins during immune surveillance and inflammation.
