UHRF1 (N-term) Mouse Monoclonal Antibody

A clear plastic resealable pouch containing a Reed Biotech product kit, with a white insert card showing the brand name and product details, photographed on a white background.

100%
Manufactured by:Reed Biotech
Save 40%ABMIUM Verified™RUO

UHRF1 (N-term) Mouse Monoclonal Antibody

UHRF1 (N-term) monoclonal antibody; host Mouse; reactivity Human, Mouse

SKU:
ABM5042982-1
Manufacturer SKU
RA12152
Product type
Primary Antibodies
TargetUHRF1 (N-term)
ApplicationsWB
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
Reed Biotech
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

ubiquitin like with PHD and ring finger domains 1(UHRF1) Homo sapiens This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014],

Key facts & specifications
Also known as
Ac2-121, AL022808, E3 ubiquitin-protein ligase UHRF1, EC 6.3.2.-, FLJ21925, Hnp95 Huhrf1, HuNp95, ICBP90, Inverted CCAAT box binding protein of 90 kDa, Inverted CCAAT box binding protein, 90-Kd, Inverted CCAAT box-binding protein of 90 kDa, Liver regeneration-related protein LRRG126, MGC138707, NP95, Nuclear phosphoprotein, 95-KD, Nuclear protein 95, Nuclear zinc finger protein Np95, RING finger protein 106, RNF106, Transcription factor ICBP90, Ubiquitin like containing PHD and RING finger domains protein 1, Ubiquitin like PHD and RING finger domain containing protein 1, Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like protein containing PHD and RING finger domains 1, Ubiquitin-like with PHD and ring finger domains 1, Ubiquitin-like, containing PHD and RING finger domains, 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, UHRF1, UHRF1_HUMAN
Host species
Mouse
Clonality
Monoclonal
Dilution range
wb 1:1000
Immunogen
Purified recombinant human UHRF1 protein fragments expressed in E.coil.
Molecular weight
90 kDa
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Form / buffer
Liquid
Quantity per pack
50 or 100 µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Manufacturer-listed application compatibility

Evidence status by application and model.

Species / reactivityWB
Human,Mouse
Identifiers & database references
Manufacturer SKU
RA12152
Gene ID
29128
UniProt accession
Q96T88
Storage, stability & shipping
Storage conditions
-20°C/1 year
Long-term storage
-20°C/1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Reed Biotech
£189.00£113.40