Manufactured by:Reed Biotech
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GTBP Monoclonal Antibody

GTBP monoclonal antibody; host Mouse; reactivity Human

SKU:
ABM5042156-1
Manufacturer SKU
RA11326
Product type
Primary Antibodies
TargetGTBP
ApplicationsWB, ELISA
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Reed Biotech
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

mutS homolog 6(MSH6) Homo sapiens This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013],

Key facts & specifications
Also known as
MSH6, GTBP, DNA mismatch repair protein Msh6, hMSH6, G/T mismatch-binding protein, GTMBP, MutS-alpha 160 kDa subunit, p160
Host species
Mouse
Clonality
Monoclonal
Dilution range
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen
Purified recombinant fragment of human GTBP expressed in E. Coli.
Purification
Affinity purification
Form / buffer
Ascitic fluid
Quantity per pack
50 or 100 µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Manufacturer-listed application compatibility

Evidence status by application and model.

Species / reactivityWBELISA
Human
Identifiers & database references
Manufacturer SKU
RA11326
Gene ID
2956
UniProt accession
P52701
Storage, stability & shipping
Storage conditions
-20°C/1 year
Long-term storage
-20°C/1 year
Storage buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Reed Biotech
£189.00£113.40