BMPER polyclonal antibody; host Rabbit; reactivity Human, Mouse
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BMP binding endothelial regulator(BMPER) Homo sapiens This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011],
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species / reactivity | WB | ELISA |
|---|---|---|
| Human,Mouse |
This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
BMPER (BMP binding endothelial regulator), also called BMP-binding endothelial regulator protein or CV-2, is a secreted extracellular modulator of bone morphogenetic protein signalling.
Biological function: BMPER is a secreted BMP-binding protein that regulates cellular responsiveness to bone morphogenetic proteins. Curated human evidence supports inhibitory effects on BMP signalling, including BMP2- and BMP4-dependent osteoblast and chondrogenic differentiation.
