ApoA-IV monoclonal antibody; host Mouse; reactivity Human
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apolipoprotein A4(APOA4) Homo sapiens Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro. [provided by RefSeq, Jul 2008],
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species / reactivity | WB | ELISA |
|---|---|---|
| Human |
This product is manufactured by Reed Biotech and sold through ABMIUM without relabelling.
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APOA4 encodes apolipoprotein A4; the mature protein apolipoprotein A-IV (ApoA-IV) is produced predominantly in the intestine and secreted in association with chylomicron particles.
Biological function: NCBI describes apolipoprotein A-IV as an intestine-derived secreted apolipoprotein associated with chylomicrons and a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. Its precise physiological function is not fully defined.
