Manufactured by:Promab
RUO

Anti-TIGIT Rabbit Polyclonal Antibody

TIGIT antibody from Promab.

SKU:
ABM417008-1
Product type
Primary antibodies
TargetTIGIT
ApplicationsWB
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Inhibitory receptor that plays a role in the modulation of immune responses. Suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells. Upon binding to its ligands PVR/CD155 or NECTIN2/CD112, which are expressed on antigen-presenting cells, sends inhibitory signals to the T-cell or NK cell.

For research use only.

Key facts & specifications
Also known as
T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain-containing protein 3; TIGIT; VSIG9; VSTM3
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This TIGIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-142 amino acids from human TIGIT.
Molecular weight
26.3 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Identifiers & database references
Gene symbol
TIGIT
Gene ID
201633
UniProt accession
Q495A1
Ensembl
ENSG00000181847
HGNC
26838
OMIM
612859
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

TIGITT cell immunoreceptor with Ig and ITIM domains

View target guide

TIGIT identifies T cell immunoreceptor with Ig and ITIM domains in Homo sapiens (Human). This target record connects NCBI Gene 201633, UniProtKB Q495A1 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
201633
UniProtKB
Q495A1
Promab
£174.20