Manufactured by:Promab
RUO

Anti-TERF2 Rabbit Polyclonal Antibody

TERF2 antibody from Promab.

SKU:
ABM414550-1
Product type
Primary antibodies
TargetTERF2
ApplicationsWB, IHC-P
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

TERF2 binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. TERF2 is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection.

For research use only.

Key facts & specifications
Also known as
Telomeric repeat-binding factor 2; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein; TERF2; TRBF2; TRF2
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This TERF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the Central region of human TERF2.
Molecular weight
59.6 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
TERF2
Gene ID
7014
UniProt accession
Q15554
Ensembl
ENSG00000132604
HGNC
11729
OMIM
602027
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20