Manufactured by:Promab
RUO

Anti-PRKCA Rabbit Polyclonal Antibody

PRKCA antibody from Promab.

SKU:
ABM403318-1
Product type
Primary antibodies
TargetPRKCA
ApplicationsWB, IHC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signalling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. PRKCA is involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle.

For research use only.

Key facts & specifications
Also known as
AAG6; PKCA; PRKACA; PKC-alpha; PRKCA; protein kinase C alpha; Protein kinase C alpha type
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB,IHC
Immunogen
Fusion protein of human PRKCA
Molecular weight
77 kDa
Technical note
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
PRKCA
Gene ID
5578
UniProt accession
P17252
Ensembl
ENSG00000154229
HGNC
9393
OMIM
176960
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PRKCAprotein kinase C alpha

View target guide

PRKCA identifies protein kinase C alpha in Homo sapiens (Human). This target record connects NCBI Gene 5578, UniProtKB P17252 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5578
UniProtKB
P17252
Promab
£174.20