Manufactured by:Promab
RUO

Anti-Phospho-TGF beta Receptor I (Ser165) Rabbit Polyclonal Antibody

Phospho-TGF beta Receptor I (Ser165) antibody from Promab.

SKU:
ABM410752-1
Product type
Primary antibodies
TargetPhospho-TGF beta Receptor I (Ser165)
ApplicationsWB, IHC, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.

For research use only.

Key facts & specifications
Also known as
TGFBR1; ALK5; SKR4; TGF-beta receptor type-1; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; Serine/threonine-protein kinase receptor R4; TGF-beta type I receptor; Transfor; transforming growth factor beta receptor 1; Phospho-TGF beta Receptor I (Ser165)
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I around the phosphorylation site of Ser165. AA range:131-180
Molecular weight
Calculated MW: 56 kDa; Observed MW: 56 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
TGFBR1
Gene ID
7046
UniProt accession
P36897
Ensembl
ENSG00000106799
HGNC
11772
OMIM
190181
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

TGFBR1transforming growth factor beta receptor 1

View target guide

TGFBR1 identifies transforming growth factor beta receptor 1 in Homo sapiens (Human). This target record connects NCBI Gene 7046, UniProtKB P36897 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
7046
UniProtKB
P36897
Promab
£174.20