Manufactured by:Promab
RUO

Anti-PAN3 (C-term) Rabbit Polyclonal Antibody

PAN3 (C-term) antibody from Promab.

SKU:
ABM413840-1
Product type
Primary antibodies
TargetPAN3 (C-term)
ApplicationsWB, IHC-P, Flow Cytometry
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

PAN3 is a regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.

For research use only.

Key facts & specifications
Also known as
PAB-dependent poly(A)-specific ribonuclease subunit PAN3 {ECO:0000255; HAMAP-Rule:MF_03181}; PAB1P-dependent poly(A)-nuclease {ECO:0000255; PAN deadenylation complex subunit 3 {ECO:0000255; hPan3; PAN3 {ECO:0000255; PAN3; poly(A) specific ribonuclease subunit PAN3; PAN2-PAN3 deadenylation complex subunit PAN3; PAN3 (C-term)
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This PAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-799 amino acids from the C-terminal region of human PAN3.
Molecular weight
95.6 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
PAN3
Gene ID
255967
UniProt accession
Q58A45
Ensembl
ENSG00000152520
HGNC
29991
OMIM
617448
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20