Manufactured by:Promab
RUO

Anti-NMB Rabbit Polyclonal Antibody

NMB antibody from Promab.

SKU:
ABM421198-1
Product type
Primary antibodies
TargetNMB
ApplicationsWB, IHC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Stimulates smooth muscle contraction. NMB induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity. NMB contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem.

For research use only.

Key facts & specifications
Also known as
Neuromedin-B; NMB; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Neuromedin B. The exact sequence is proprietary.
Molecular weight
16 kD
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
NMB
Gene ID
4828
UniProt accession
P08949
Ensembl
ENSG00000197696
HGNC
7842
OMIM
162340
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

GPNMBglycoprotein nmb

View target guide

GPNMB identifies glycoprotein nmb in Homo sapiens (Human). This target record connects NCBI Gene 10457, UniProtKB Q14956 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
10457
UniProtKB
Q14956
Promab
£174.20