Manufactured by:Promab
RUO

Anti-MIP-3α Rabbit Polyclonal Antibody

MIP-3α antibody from Promab.

SKU:
ABM420417-1
Product type
Primary antibodies
TargetMIP-3α
ApplicationsIHC
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

CCL20 acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions. The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases.

For research use only.

Key facts & specifications
Also known as
C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into: CCL20(1-67); CCL20(1-64); CCL20(2-70)]; CCL20; C-C motif chemokine ligand 20; C-C motif chemokine 20; MIP-3α
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
IHC: 1/50-300
Immunogen
Synthetic peptide from human protein at AA range: 31-80
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Identifiers & database references
Gene symbol
CCL20
Gene ID
6364
UniProt accession
P78556
Ensembl
ENSG00000115009
HGNC
10619
OMIM
601960
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CCL20C-C motif chemokine ligand 20

View target guide

CCL20 identifies C-C motif chemokine ligand 20 in Homo sapiens (Human). This target record connects NCBI Gene 6364, UniProtKB P78556 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
6364
UniProtKB
P78556
Promab
£174.20