Manufactured by:Promab
RUO

Anti-IDE Rabbit Polyclonal Antibody

IDE antibody from Promab.

SKU:
ABM403169-1
Product type
Primary antibodies
TargetIDE
ApplicationsWB, IHC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

IDE plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signalling. Substrate binding induces important conformation changes, making it possible to bind and degrade larger substrates, such as insulin. IDE contributes to the regulation of peptide hormone signalling cascades and regulation of blood glucose homeostasis via its role in the degradation of insulin, glucagon and IAPP.

For research use only.

Key facts & specifications
Also known as
INSULYSIN; IDE; insulin degrading enzyme
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB,IHC
Immunogen
Fusion protein of human IDE
Molecular weight
118 kDa
Technical note
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
IDE
Gene ID
3416
UniProt accession
P14735
Ensembl
ENSG00000119912
HGNC
5381
OMIM
146680
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

IDEinsulin degrading enzyme

View target guide

IDE identifies insulin degrading enzyme in Homo sapiens (Human). This target record connects NCBI Gene 3416, UniProtKB P14735 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
3416
UniProtKB
P14735
Promab
£174.20