Manufactured by:Promab
RUO

Anti-DNMT3L Rabbit Polyclonal Antibody

DNMT3L antibody from Promab.

SKU:
ABM403089-1
Product type
Primary antibodies
TargetDNMT3L
ApplicationsIHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Catalytically inactive regulatory factor of DNA methyltransferases that can either promote or inhibit DNA methylation depending on the context. DNMT3L is essential for the function of DNMT3A and DNMT3B: activates DNMT3A and DNMT3B by binding to their catalytic domain. DNMT3L acts by accelerating the binding of DNA and S-adenosyl-L-methionine (AdoMet) to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases.

For research use only.

Key facts & specifications
Also known as
DNMT3L; DNA methyltransferase 3 like; DNA
Host species
Rabbit
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
IHC
Immunogen
Fusion protein of human DNMT3L
Technical note
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
DNMT3L
Gene ID
29947
UniProt accession
Q9UJW3
Ensembl
ENSG00000142182
HGNC
2980
OMIM
606588
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Promab
£174.20