APOC3 antibody from Promab.
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APOC3 is a component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. APOC3 plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs).
For research use only.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IHC-P | IHC-F | IF/ICC | Flow Cytometry | ELISA | IP | ChIP |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by Promab and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
APOC3 (apolipoprotein C3) encodes apolipoprotein C-III (ApoC-III), a component of triglyceride-rich lipoproteins including VLDL and chylomicrons and also of HDL. APOC3 is a key regulator of triglyceride homeostasis through effects on lipoprotein production, lipolysis and remnant clearance.
Biological function: Apolipoprotein C-III regulates triglyceride-rich lipoprotein metabolism at several steps. NCBI and reviewed UniProt describe APOC3 as promoting hepatic VLDL1 assembly and secretion, inhibiting lipoprotein lipase-mediated triglyceride hydrolysis, and delaying hepatic clearance of triglyceride-rich lipoprotein remnants.
