Manufactured by:Promab
RUO

Anti-Phospho-ULK1(S556) Rabbit Monoclonal Antibody

Phospho-ULK1(S556) antibody from Promab.

SKU:
ABM408927-1
Product type
Primary antibodies
TargetPhospho-ULK1(S556)
ApplicationsWB, IF/ICC
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

ULK1 is a serine/threonine-protein kinase involved in autophagy in response to starvation. ULK1 acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. ULK1 forms part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR.

For research use only.

Key facts & specifications
Also known as
ATG1; ATG1A; hATG1; ULK1; UNC51; p-ULK1 (S556); unc-51 like autophagy activating kinase 1; Serine/threonine-protein kinase ULK1; Phospho-ULK1(S556)
Host species
Rabbit
Clonality
Monoclonal
Conjugation
Unconjugated
Immunogen
A synthesized peptide derived from human ULK1 around the phosphorylation site of S556
Molecular weight
Calculated MW: 113 kDa ; Observed MW: 130150 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Identifiers & database references
Gene symbol
ULK1
Gene ID
8408
UniProt accession
O75385
Ensembl
ENSG00000177169
HGNC
12558
OMIM
603168
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

ULK1unc-51 like autophagy activating kinase 1

View target guide

ULK1 identifies unc-51 like autophagy activating kinase 1 in Homo sapiens (Human). This target record connects NCBI Gene 8408, UniProtKB O75385 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
8408
UniProtKB
O75385
Promab
$210.00