Manufactured by:Promab
RUO

Anti-Phospho-AMPK alpha 1 (Ser496) Rabbit Monoclonal Antibody

Phospho-AMPK alpha 1 (Ser496) antibody from Promab.

SKU:
ABM410610-1
Product type
Primary antibodies
TargetPhospho-AMPK alpha 1 (Ser496)
ApplicationsWB, IF/ICC, IP
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.

For research use only.

Key facts & specifications
Also known as
PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1; Phospho-AMPK alpha 1 (Ser496)
Host species
Rabbit
Clonality
Monoclonal
Conjugation
Unconjugated
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser496 of human AMPK alpha 1
Molecular weight
Calculated MW: 64 kDa; Observed MW: 64 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Identifiers & database references
Gene symbol
PRKAA1
Gene ID
5562
UniProt accession
Q13131
Ensembl
ENSG00000132356
HGNC
9376
OMIM
602739
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PRKAA1protein kinase AMP-activated catalytic subunit alpha 1

View target guide

PRKAA1 identifies protein kinase AMP-activated catalytic subunit alpha 1 in Homo sapiens (Human). This target record connects NCBI Gene 5562, UniProtKB Q13131 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
5562
UniProtKB
Q13131
Promab
£174.20