Manufactured by:ProteoGenix
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T10B9.1A-31 Biosimilar – Anti-T cell receptor mAb – Research Grade

T10B9.1A-31 Biosimilar – Anti-T cell receptor mAb – Research Grade from ProteoGenix; catalogue PX-TA1089; research use only.

SKU:
ABM134945-1
Manufacturer SKU
PX-TA1089
Product type
Primary Antibodies
TargetT10B9.1A-31 Biosimilar – Anti-T cell receptor mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

The Structure of T10B9.1A-31 Biosimilar

T10B9.1A-31 Biosimilar is a monoclonal antibody (mAb) that is designed to mimic the structure and function of the T cell receptor (TCR). It is a research-grade antibody that is produced in a biosimilar form, meaning it is highly similar to the original T10B9.1A-31 antibody in terms of structure and function. The biosimilar form of T10B9.1A-31 is produced using recombinant DNA technology, where the gene for the antibody is inserted into a host cell, allowing it to be replicated and produced in large quantities.

The T10B9.1A-31 Biosimilar antibody is composed of two heavy chains and two light chains, which are held together by disulfide bonds. The heavy chains are made up of constant and variable regions, while the light chains contain only variable regions. The variable regions of both the heavy and light chains are responsible for binding to the specific target molecule, which in this case is the TCR.

The Activity of T10B9.1A-31 Biosimilar

T10B9.1A-31 Biosimilar is a highly specific antibody that targets the T cell receptor, a protein found on the surface of T cells. T cells are a type of white blood cell that plays a crucial role in the immune system by recognizing and attacking foreign invaders such as viruses, bacteria, and cancer cells. The TCR is responsible for recognizing specific antigens, which are molecules found on the surface of these foreign invaders.

When T10B9.1A-31 Biosimilar binds to the TCR, it blocks the interaction between the TCR and its target antigen. This prevents the activation of the T cell and subsequently inhibits its ability to mount an immune response. This activity is particularly useful in conditions where the immune system is overactive, such as autoimmune diseases, as it helps to reduce inflammation and tissue damage.

The Application of T10B9.1A-31 Biosimilar

T10B9.1A-31 Biosimilar has potential therapeutic applications in a wide range of diseases. As mentioned earlier, it can be used to treat autoimmune diseases by inhibiting the activity of T cells. This includes conditions such as rheumatoid arthritis, multiple sclerosis, and psoriasis.

In addition, T10B9.1A-31 Biosimilar can also be used in the treatment of certain types of cancer. T cells play a crucial role in the body’s immune response against cancer cells, and by targeting the TCR, T10B9.1A-31 Biosimilar can help to suppress the growth and spread of cancer cells. This makes it a promising candidate for cancer immunotherapy, which aims to boost the body’s own immune system to fight cancer.

Furthermore, T10B9.1A-31 Biosimilar can also be used in research settings to study the role of T cells in various diseases and to develop new treatments. Its highly specific targeting of the TCR makes it a valuable tool for understanding the mechanisms of T cell activation and regulation.

Conclusion

In summary, T10B9.1A-31 Biosimilar is a research-grade monoclonal antibody that mimics the structure and function of the T cell receptor. Its activity as a TCR inhibitor makes it a promising candidate for the treatment of autoimmune diseases and cancer, as well as a valuable tool for research purposes. With its potential to improve patient outcomes and advance our understanding of the immune system, T10B9.1A-31 Biosimilar is a promising addition to the field of antibody therapeutics.

ProteoGenix catalogue number PX-TA1089. For research use only.

Target: T10B9.1A-31 Biosimilar – Anti-T cell receptor mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
T10B9.1A-31,MEDI-500,T10B9,T10B9.1A-31,T cell receptor,anti-T cell receptor
Clonality
Monoclonal
Isotype
IgM-kappa
Source organism
Mouse
Sequence
IQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKTVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESSCDVKLVEKSFETDTNLNFQNLSVIGFRILLLKVAGFNLLMTLRLWSS
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
T10B9.1A-31 Biosimilar – Anti-T cell receptor mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1089
UniProt accession
P01848
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£149.00£119.20