Manufactured by:ProteoGenix
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Recombinant Human PCBP2 Protein, N-His

Recombinant Human PCBP2 Protein, N-His from ProteoGenix; catalogue ARO-P11581; research use only.

SKU:
ABM142018-1
Manufacturer SKU
ARO-P11581
Product type
Recombinant Proteins
Expression systemProkaryotic expression

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Recombinant Human PCBP2 Protein is a highly versatile and important protein that plays a crucial role in various cellular processes. This protein is produced through recombinant DNA technology, making it a valuable tool for scientific research and applications. In this article, we will provide a detailed description of the structure, activity, and applications of Recombinant Human PCBP2 Protein.

Structure of Recombinant Human PCBP2 Protein

Recombinant Human PCBP2 Protein is composed of 356 amino acids and has a molecular weight of approximately 40 kDa. It belongs to the poly(rC)-binding protein (PCBP) family and is also known as hnRNP E2. The protein consists of three RNA-binding domains (RBDs) that are essential for its function. These RBDs are highly conserved and are responsible for the protein’s ability to bind to RNA molecules.

Activity of Recombinant Human PCBP2 Protein

The main function of Recombinant Human PCBP2 Protein is to regulate the post-transcriptional processing of RNA molecules. It binds to specific sequences on RNA and modulates their stability, translation, and localization. This protein has been shown to interact with a variety of RNA molecules, including mRNAs, microRNAs, and long non-coding RNAs.

Additionally, Recombinant Human PCBP2 Protein has been found to play a role in various cellular processes such as cell proliferation, differentiation, and apoptosis. It has also been implicated in the regulation of viral replication and pathogenesis. Furthermore, studies have shown that this protein is involved in the development and progression of various diseases, including cancer and viral infections.

Applications of Recombinant Human PCBP2 Protein

Recombinant Human PCBP2 Protein has a wide range of applications in the field of molecular biology and biotechnology. Its ability to bind to RNA molecules with high specificity and affinity makes it a valuable tool for studying RNA-protein interactions. This protein can be used in various techniques such as RNA pull-down assays, RNA immunoprecipitation, and RNA crosslinking experiments.

In addition, Recombinant Human PCBP2 Protein has potential diagnostic and therapeutic applications. Its involvement in various diseases makes it a potential biomarker for disease diagnosis and prognosis. Furthermore, this protein can be targeted for the development of novel therapeutic strategies for diseases such as cancer and viral infections.

Moreover, Recombinant Human PCBP2 Protein has been used in the production of RNA-based therapeutics. Its ability to bind to specific RNA sequences can be utilized to deliver therapeutic molecules to target cells. This protein has also been used in the development of RNA-based vaccines, which have shown promising results in preclinical studies.

Conclusion

Recombinant Human PCBP2 Protein is a highly versatile and important protein that plays a crucial role in various cellular processes. Its structure, activity, and applications make it a valuable tool for scientific research and potential therapeutic applications. With ongoing research and advancements in recombinant protein technology, the potential of Recombinant Human PCBP2 Protein in various fields continues to grow, making it a promising candidate for future studies and applications.

ProteoGenix catalogue number ARO-P11581. For research use only.

Host: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 19.62 kDa; Fragment: Asn11-Ser173; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Heterogeneous nuclear ribonucleoprotein E2, Alpha-CP2, hnRNP E2, Poly(rC)-binding protein 2, PCBP2
Host species
E. coli
Source organism
Human
Molecular weight
19.62 kDa
Sequence fragment
Asn11-Ser173
Sequence
NVTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCPERIITLAGPTNAIFKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQS
Technical note
For research use only.
Identifiers & database references
Manufacturer SKU
ARO-P11581
UniProt accession
Q15366
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Shipped at
Dry Ice
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£199.00£159.20