Manufactured by:ProteoGenix
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Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade

Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade from ProteoGenix; catalogue PX-TA1690; research use only.

SKU:
ABM134358-1
Manufacturer SKU
PX-TA1690
Product type
Primary Antibodies
TargetNipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade

Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade: A Revolutionary Antibody Nipocalimab Biosimilar, also known as Anti-FCGRT mAb, is a groundbreaking antibody that has the potential to revolutionize the field of therapeutics. This biosimilar is a monoclonal antibody that specifically targets the FCGRT protein, making it a highly specific and effective therapeutic agent.

Structure of Nipocalimab Biosimilar

Nipocalimab Biosimilar is a recombinant humanized IgG1 monoclonal antibody. It is composed of two heavy chains and two light chains, making it a Y-shaped molecule. The heavy chains consist of four constant regions (CH1, CH2, CH3, and CH4) and one variable region (VH). The light chains consist of one constant region (CL) and one variable region (VL). These variable regions are responsible for the specific binding to the FCGRT protein.

Activity of Nipocalimab Biosimilar

The main activity of Nipocalimab Biosimilar is its ability to bind to the FCGRT protein. FCGRT, also known as neonatal Fc receptor, is a protein that plays a crucial role in the recycling of immunoglobulin G (IgG) antibodies in the body. By binding to FCGRT, Nipocalimab Biosimilar blocks the recycling of IgG antibodies, leading to a decrease in their levels in the body. This, in turn, can have a therapeutic effect on various diseases.

Application of Nipocalimab Biosimilar

Nipocalimab Biosimilar has shown promising results in preclinical studies for the treatment of various diseases. Its main application is in the treatment of autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis. By reducing the levels of IgG antibodies, Nipocalimab Biosimilar can help alleviate the symptoms of these diseases and improve the overall health of patients.

Additionally, Nipocalimab Biosimilar has also shown potential in the treatment of cancer. By targeting the FCGRT protein, it can enhance the body’s immune response against cancer cells and potentially improve the efficacy of other cancer therapies.

Benefits of Nipocalimab Biosimilar

Nipocalimab Biosimilar has several advantages over traditional therapies. Firstly, its highly specific binding to the FCGRT protein minimizes the risk of off-target effects and reduces the potential for adverse reactions. Secondly, as a biosimilar, it is a more cost-effective option compared to other monoclonal antibodies on the market. Finally, its potential to treat a wide range of diseases makes it a versatile and valuable therapeutic agent.

Future of Nipocalimab Biosimilar

The future of Nipocalimab Biosimilar looks promising, with ongoing clinical trials in various autoimmune diseases and cancer. If successful, it has the potential to become a game-changer in the field of therapeutics, providing a more targeted and cost-effective treatment option for patients.

Conclusion

Nipocalimab Biosimilar, also known as Anti-FCGRT mAb, is a highly specific and effective antibody that targets the FCGRT protein. Its potential to treat various diseases, along with its cost-effectiveness, make it a promising therapeutic option for patients. With ongoing research and clinical trials, Nipocalimab Biosimilar has the potential to revolutionize the field of therapeutics and improve the lives of many individuals.

ProteoGenix catalogue number PX-TA1690. For research use only.

Target: Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg, 10mg, 25mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Nipocalimab,IMMUNOGLOBULIN G1, ANTI-(HUMAN NEONATAL FC RECEPTOR) (HUMAN MONOCLONAL M281 .GAMMA.-1 CHAIN), DISULFIDE WITH HUMAN MONOCLONAL M281 .LAMBDA.-CHAIN, DIMER, M-281,FCGRT,anti-FCGRT
Clonality
Monoclonal
Isotype
IgG1, lambda
Source organism
CAS 2211985-36-1
Sequence
MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNVIPATA
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Nipocalimab Biosimilar – Anti-FCGRT mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1690
UniProt accession
P55899
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£79.00£63.20