Manufactured by:ProteoGenix
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Ivonescimab Biosimilar – Anti-VEGF & PD1 mAb – Research Grade

Ivonescimab Biosimilar – Anti-VEGF & PD1 mAb – Research Grade from ProteoGenix; catalogue PX-TA1763; research use only.

SKU:
ABM134289-1
Manufacturer SKU
PX-TA1763
Product type
Primary Antibodies
TargetIvonescimab Biosimilar – Anti-VEGF & PD1 mAb – Research Grade
ApplicationsELISA, WB, Flow Cytometry
Expression systemXtenCHO

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

What is Ivonescimab?

Ivonescimab (AK112) is an antibody developed to target both PD-1 and VEGF pathways, two key mechanisms involved in immune regulation and angiogenesis. It is widely studied in immuno-oncology research for its ability to modulate tumor immune responses while impacting vascular development.

Mechanism of Action

This ivonescimab antibody is used in research to explore combined inhibition of PD-1-mediated immune checkpoint signaling and VEGF-driven angiogenesis. Such dual pathway targeting is of particular interest in studies of tumor progression and therapeutic response.

Applications

  • Immuno-oncology research
  • PD-1 immune checkpoint studies
  • Angiogenesis and VEGF pathway analysis
  • Combination therapy research
  • Preclinical evaluation of antibody-based approaches

Key Features

  • Targets PD-1 and VEGF-related pathways
  • Suitable for advanced research applications
  • Consistent performance and reproducibility
  • Research-grade biosimilar format

About PD-1 and VEGF targeting

PD-1 is a key immune checkpoint receptor involved in regulating T-cell activity, while VEGF plays a central role in angiogenesis. Targeting both pathways is widely investigated in oncology research to better understand tumor immune evasion and vascular development.

Ivonescimab Antibody Price and Cost

The price of ivonescimab antibody depends on the required format, quantity, and research specifications. ProteoGenix provides high-quality biosimilars at competitive cost, ensuring accessibility for research applications.

For detailed pricing or bulk orders, you can request a quote directly from our team.

Need a tailored antibody solution?

If your research requires specific antibody formats or optimized targeting strategies, custom antibody development solutions can support advanced experimental needs.

ProteoGenix catalogue number PX-TA1763. For research use only.

Target: Ivonescimab Biosimilar – Anti-VEGF & PD1 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Buffer: PBS buffer PH7.5; Applications: ELISA, WB, Flow Cyt.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Ivonescimab,AK 112, AK-112, AK112,VEGF & PD1,anti-VEGF & PD1
Clonality
Monoclonal
Isotype
IgG1-kappa-[scFv]2
Source organism
CAS: 2428381-53-5
Sequence
MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLGCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Ivonescimab Biosimilar – Anti-VEGF & PD1 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1763
UniProt accession
P15692 & Q15116
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£149.00£119.20