Manufactured by:ProteoGenix
Save 20%RUO

Ciduvectamig Biosimilar – Anti-TMEFF2, CD3E mAb – Research Grade

Ciduvectamig Biosimilar – Anti-TMEFF2, CD3E mAb – Research Grade from ProteoGenix; catalogue PX-TA2055; research use only.

SKU:
ABM134008-1
Manufacturer SKU
PX-TA2055
Product type
Primary Antibodies
TargetCiduvectamig Biosimilar – Anti-TMEFF2, CD3E mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>90% by SDS-PAGE.

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Ciduvectamig Biosimilar: A Powerful Antibody Targeting TMEFF2 and CD3E for Therapeutic Use

Introduction

Ciduvectamig Biosimilar is a novel antibody that has been developed as a biosimilar version of the existing anti-TMEFF2 and CD3E monoclonal antibodies. This biosimilar is designed to target and bind to both TMEFF2 and CD3E, making it a powerful therapeutic tool for various diseases. In this article, we will discuss the structure, activity, and potential applications of Ciduvectamig Biosimilar in more detail.

Structure of Ciduvectamig Biosimilar

Ciduvectamig Biosimilar is a recombinant humanized monoclonal antibody that is produced using advanced biotechnology techniques. It is composed of two heavy chains and two light chains, each containing a variable region and a constant region. The variable regions of the antibody are responsible for binding to the target molecules, TMEFF2 and CD3E.

Activity of Ciduvectamig Biosimilar

Ciduvectamig Biosimilar has a dual mechanism of action, targeting both TMEFF2 and CD3E. TMEFF2 is a transmembrane protein that is overexpressed in many types of cancer, including breast, lung, and prostate cancer. By binding to TMEFF2, Ciduvectamig Biosimilar inhibits its activity and prevents the growth and spread of cancer cells.

CD3E, on the other hand, is a protein found on the surface of T cells. It plays a crucial role in the activation and proliferation of T cells, which are important for the immune response against infections and cancer. Ciduvectamig Biosimilar binds to CD3E and modulates its activity, leading to the activation of T cells and enhancing the immune response.

Applications of Ciduvectamig Biosimilar

Ciduvectamig Biosimilar has shown great potential in the treatment of various diseases, particularly cancer. Its ability to target both TMEFF2 and CD3E makes it a promising therapeutic option for different types of cancer. It can be used as a monotherapy or in combination with other cancer treatments, such as chemotherapy and radiation therapy.

Moreover, Ciduvectamig Biosimilar has also shown promise in the treatment of autoimmune diseases. By modulating the activity of CD3E and activating T cells, it can help regulate the immune response and reduce inflammation in diseases such as rheumatoid arthritis and multiple sclerosis.

Additionally, Ciduvectamig Biosimilar can also be used in research settings as a research-grade antibody. Its high specificity and potency make it a valuable tool for studying the role of TMEFF2 and CD3E in various diseases and for developing new treatments.

Conclusion

In conclusion, Ciduvectamig Biosimilar is a powerful antibody that targets both TMEFF2 and CD3E. Its unique structure and dual mechanism of action make it a promising therapeutic option for various diseases, particularly cancer and autoimmune diseases. Its potential applications in both clinical and research settings make it a valuable addition to the field of biotechnology and medicine.

ProteoGenix catalogue number PX-TA2055. For research use only.

Target: Ciduvectamig Biosimilar – Anti-TMEFF2, CD3E mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >90% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-TMEFF2, CD3E
Clonality
Monoclonal
Isotype
IgG4-kappa/lambda2
Source organism
Human
Sequence
MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Ciduvectamig Biosimilar – Anti-TMEFF2, CD3E mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2055
UniProt accession
Q9UIK5 & P07766
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£149.00£119.20