Anti-Dog CD22 Polyclonal Antibody from ProteoGenix; catalogue ARO-A22094; research use only.
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Anti-Dog CD22 Polyclonal Antibody
The Anti-Dog CD22 Polyclonal Antibody is a high-quality research tool specifically designed for the detection and analysis of CD22 protein in canine samples. CD22, also known as Siglec-2, is a transmembrane glycoprotein that is primarily expressed on the surface of B cells. This protein plays a crucial role in regulating B cell activation and survival, making it a valuable target for research in the field of immunology and cancer biology.
This polyclonal antibody is produced in rabbits using a highly purified recombinant CD22 protein as the immunogen. It has been extensively validated for its specificity and sensitivity in various assays, including Western blotting, immunohistochemistry, and flow cytometry. The Anti-Dog CD22 Polyclonal Antibody has been shown to specifically recognize the CD22 protein in a variety of canine tissues and cell lines, making it a reliable tool for canine research.
One of the main applications of this antibody is in the study of B cell-related diseases, such as B cell lymphomas and leukemias. CD22 is known to be overexpressed in these types of cancers, and targeting it with specific antibodies has shown promising results in preclinical studies. The Anti-Dog CD22 Polyclonal Antibody can be used to investigate the role of CD22 in these diseases and potentially aid in the development of new therapeutic strategies.
In addition to cancer research, this antibody can also be used in studies of autoimmune disorders. CD22 has been linked to the regulation of autoreactive B cells, and its dysfunction has been associated with autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. The Anti-Dog CD22 Polyclonal Antibody can help researchers better understand the role of CD22 in these conditions and potentially identify new targets for treatment.
Experimental use cases for this antibody include the detection of CD22 expression in canine tumor samples, the evaluation of CD22-targeted therapies in preclinical models, and the investigation of CD22-mediated signaling pathways in B cells. Its high specificity and sensitivity make it a valuable tool for these and other research applications.
In summary, the Anti-Dog CD22 Polyclonal Antibody is a reliable and specific tool for the detection and analysis of CD22 protein in canine samples. With its potential applications in cancer research and autoimmune disorders, this antibody is a valuable addition to any biotech laboratory. Order now and advance your research with confidence.
ProteoGenix catalogue number ARO-A22094. For research use only.
Target: B-cell receptor CD22 isoform X1; CD22; Clonality: Polyclonal Antibody; Reactivity: Dog; Applications: IHC, ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Dog |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
