ELISA Kit geliefert von Boster Bio
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NTRK3 (Neurotrophe Tyrosinkinase-Rezeptor Typ 3), auch bekannt als TRKC, ist ein Protein, das beim Menschen vom NTRK3-Gen kodiert wird. Durch PCR-Analyse eines somatischen Zellhybridpanels und durch Fluoreszenz-in-situ-Hybridisierung mit dem cDNA-Klon wurde das NTRK3-Gen auf 15q24-q25 kartiert. TRKC, ein Mitglied der TRK-Familie von Tyrosinproteinkinase-Genen. Sie fanden heraus, dass TRKC bevorzugt im Gehirn exprimiert wird; in-situ-Hybridisierungsstudien zeigten Transkripte im Hippocampus, im zerebralen Kortex und in der Körnerzellschicht des Kleinhirns. Durch funktionelle Studien in HeLa-Zellen regulieren 5 miRNAs die verkürzte Form von NTRK3.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Empfindlichkeit | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände und Zelllysate. |
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NTRK3 identifies neurotrophic receptor tyrosine kinase 3 in Homo sapiens (Human). This target record connects NCBI Gene 4916, UniProtKB Q16288 and related ABMIUM catalogue products.
