Manufactured by:Promab
RUO

Anti-eIF2A Mouse Monoclonal Antibody

eIF2A antibody, clone 1E7 from Promab.

SKU:
ABM410826-1
Product type
Primary antibodies
TargeteIF2A
ApplicationsWB, IF/ICC, IP
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Promab
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Member of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex (43S PIC). Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex.

For research use only.

Key facts & specifications
Also known as
EIF2S1; EIF2A; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha
Host species
Mouse
Clonality
Monoclonal
Clone number
1E7
Conjugation
Unconjugated
Immunogen
Purified recombinant human eIF2α protein fragments expressed in E.coli.
Molecular weight
Calculated MW: 36 kDa; Observed MW: 36 kDa
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIPChIP
Human
Mouse
Rat
Identifiers & database references
Gene symbol
EIF2S1
Gene ID
1965
UniProt accession
P05198
Ensembl
ENSG00000134001
HGNC
3265
OMIM
603907
Storage, stability & shipping
Short-term storage
4°C (short term)
Long-term storage
-20°C (long term); aliquot and avoid repeated freeze-thaw cycles
Storage buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Aliquoting guidance
Aliquot to avoid repeated freeze-thaw.
Compliance & documents
CE marked
No
Frequently asked questions
Who manufactured this product?

This product is manufactured by Promab and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

EIF2S1eukaryotic translation initiation factor 2 subunit alpha

View target guide

EIF2S1 identifies eukaryotic translation initiation factor 2 subunit alpha in Homo sapiens (Human). This target record connects NCBI Gene 1965, UniProtKB P05198 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
1965
UniProtKB
P05198
Promab
£174.20