ELISA-Kit geliefert von Boster Bio
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Interleukin-2 (IL2), früher als T-Zell-Wachstumsfaktor bezeichnet, ist ein stark immunregulatorisches Lymphokin, das von Lektin- oder Antigen-aktivierten T-Zellen produziert wird. Es wird nicht nur von reifen T-Lymphozyten bei Stimulation produziert, sondern auch konstitutiv von bestimmten T-Zell-Lymphom-Zelllinien. Das Lymphokin Interleukin-2 (IL-2) ist verantwortlich für den autokrinen Zellzyklusfortschritt und die Regulation von Immunantworten. Die IL-2-Expression in reifen Thymozyten und T-Zellen wird durch monoallelische Expression streng kontrolliert. IL-2 kann als Wachstumshormon für B- und T-Lymphozyten wirken. Das menschliche Gen für Interleukin 2 (IL2) ist auf Chromosom 4 lokalisiert. Maus-IL-2 enthält in reifer Form 149 Aminosäuren mit einer Molekülmasse von 17,2 KDa.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum und Plasma (Heparin | ||||
| EDTA | ||||
| Citrat). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
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IL2 identifies interleukin 2 in Homo sapiens (Human). This target record connects NCBI Gene 3558, UniProtKB P60568 and related ABMIUM catalogue products.
Biological function: IL2 is a cytokine produced mainly by activated T cells that supports immune-cell proliferation, differentiation and survival. It signals through IL2 receptor complexes to activate JAK-STAT, PI3K and MAPK pathways, supporting T-cell, regulatory T-cell, NK-cell and B-cell responses.
