ELISA-Kit geliefert von Boster Bio
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Insulin-like growth factor-binding protein 2 (IGFBP2), auch IBP2 genannt, ist ein Protein, das beim Menschen vom IGFBP2-Gen kodiert wird. Es ist auf 2q35 kartiert. Strukturelle Analysen zeigten, dass das IGFBP2-Gen aus 4 Exons mit 3 Introns von 27,0, 1,0 und 1,9 kb Länge besteht. Von metastatischen Zellen sezerniertes IGFBP2 rekrutiert Endothelzellen, indem es die IGF1-vermittelte Aktivierung des IGF-Typ-I-Rezeptors auf Endothelzellen moduliert. Die Signalwege IGFBP2/IGF1/IGF1R und GAS6/MERTK sind Regulatoren der krebsvermittelten endothelialen Rekrutierung.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Zelllysate | ||||
| Serum und Plasma (Heparin | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
IGFBP2 identifies insulin like growth factor binding protein 2 in Homo sapiens (Human). This target record connects NCBI Gene 3485, UniProtKB P18065 and related ABMIUM catalogue products.
