ELISA-Kit geliefert von Boster Bio
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Dipeptidylpeptidase-4 (DPP4), auch bekannt als Adenosin-Desaminase-komplexbildendes Protein 2 oder CD26 (Cluster of Differentiation 26), ist ein Protein, das beim Menschen vom DPP4-Gen kodiert wird. Mittels Fluoreszenz-in-situ-Hybridisierung wurde das CD26-Gen auf 2q24.3 kartiert. DPP4 spielt eine wichtige Rolle im Glukosestoffwechsel. Es ist verantwortlich für den Abbau von Inkretinen wie GLP-1. Darüber hinaus scheint es als Suppressor bei der Entwicklung von Krebs und Tumoren zu wirken. CD26/DPP4 spielt eine wichtige Rolle in der Tumorbiologie und ist als Marker für verschiedene Krebsarten nützlich, wobei seine Spiegel entweder auf der Zelloberfläche oder im Serum bei einigen Neoplasmen erhöht und bei anderen verringert sind.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Zelllysate | ||||
| Serum und Plasma (Heparin | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
DPP4 identifies dipeptidyl peptidase 4 in Homo sapiens (Human). This target record connects NCBI Gene 1803, UniProtKB P27487 and related ABMIUM catalogue products.
Biological function: Dipeptidyl peptidase 4 (DPP4; CD26/DPP IV) is a type II transmembrane serine peptidase that removes N-terminal dipeptides from susceptible peptides and also functions as a cell-surface signalling and costimulatory protein. It is studied in incretin metabolism, glucose homeostasis and immune regulation.
