ELISA-Kit geliefert von Boster Bio
Know who made it. See the evidence. Buy through one marketplace.
Alpha-Fetoprotein (AFP) ist ein Protein der Albuminoid-Superfamilie, das im Fötus hauptsächlich von der Leber, dem Dottersack und Geweben gastrointestinalen Ursprungs synthetisiert wird. Dieses Gen ist auf 5 E1; 5 44,77 cM kartiert. AFP fungiert als Trägerprotein für Steroide, Bilirubin, Fettsäuren, Retinoide und Flavonoide. Darüber hinaus kann es immunsuppressive Aktivität ausüben, Zellproliferation und Apoptose regulieren, intrazelluläre Signalgebung initiieren und zur Zellinvasion beitragen. Veränderte Konzentrationen sowohl des fetalen als auch des mütterlichen AFP wurden mit Hypothyreose, Autoimmunerkrankungen und Herzfehlern in Verbindung gebracht. Niedrige mütterliche Serum-AFP-Spiegel sind mit einer höheren Inzidenz von Down-Syndrom assoziiert, während höhere Spiegel mit Spina bifida und Anenzephalie verbunden sind. Erhöhte AFP-Spiegel gehen auch mit Leber-, Magen- und Keimzelltumoren einher.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Sample compatibility evidence using the same validation key.
| Sample type | Probenkompatibilität | Assay-Bereich | Sensitivität | Spezifität |
|---|---|---|---|---|
| Zellkulturüberstände | ||||
| Serum und Plasma (Heparin | ||||
| EDTA). |
This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
AFP (alpha fetoprotein; alpha-fetoprotein) encodes a major fetal plasma protein produced predominantly by the yolk sac and fetal liver. An albumin-family protein, AFP binds fatty acids, bilirubin and several metal ions and is widely studied in fetal development and liver biology.
Biological function: Alpha-fetoprotein (AFP) is a secreted fetal plasma protein structurally related to serum albumin. It binds fatty acids, bilirubin, copper and nickel and functions as a carrier protein during fetal life, with high production by the yolk sac and fetal liver before expression falls after birth.
